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SUMMARY:Yang Yang (UF Biostatistics)
DESCRIPTION:Statistical Adjustment for Reporting Bias in Surveillance Data of Infectious Diseases\nReporting bias is common in the surveillance of infectious diseases and takes different forms. A typical example is that outbreaks are investigated only if the number of cases exceeds a prespecified threshold. Another example is that most outbreak investigations only survey cases\, ignoring individuals who are at risk but not infected\, to which we refer as a missing denominator problem. Such bias\, if left unaddressed\, can lead to erroneous estimation of key epidemiological parameters. To adjust for the selection bias associated with reporting threshold\, the likelihood for the transmission dynamic need to be conditioned on the observation that final size of the outbreak exceeds the threshold. However\, traditional final size algorithms soon become numerically unstable even for moderate sizes. For the missing denominator problem\, branching processes are often used\, but the assumption of independent offspring distributions is questionable\, especially in small close contact groups. We propose methods for addressing these challenges. Interestingly\, our solution to the missing denominator problem relies on the final size approach to the reporting threshold problem. We will discuss simulation results for validating these methods and their application to real surveillance data of influenza and MERS-CoV.
URL:https://biomath.math.ufl.edu/event/yang-yang-uf-biostatistics/
LOCATION:Zoom
CATEGORIES:Fall 2021
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DTSTART;TZID=America/New_York:20211213T120000
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UID:1553-1639396800-1639665000@biomath.math.ufl.edu
SUMMARY:Southeast Center for Mathematics and Biology 4th Annual Symposium
DESCRIPTION:Join us for a lively exploration of the math-bio interface\nThe Symposium will host daily panel discussion about important issues in math-bio research and traineeship. How can we productively embed ourselves in a second discipline? What paths have led to successful math-bio careers in academia? In industry? \nSupport the next generation of math-bio researchers\nFollowing each panel\, the Symposium will spotlight work being done by junior researchers from all 4 NSF-Simons MathBioSys research centers. Come support these young scientists who are forging new connections at the interface between mathematics and the bio-sciences! \nFeaturing plenary lecture by Belinda Akpa\nSCMB is happy to feature Belinda Akpa\, senior scientist at Oak Ridge National Laboratory\, as the Symposium’s plenary speaker. Akpa\, who holds a joint appointment as Associate Professor of Chemical and Biomedical Engineering at UTK\, will speak on “making the most of ‘tiny data’ in systems biomedicine” in the 12pm plenary session on Thursday 12/16. \nContribute your own work to our poster session\nFollowing the plenary session\, the Symposium will host a poster session via spatial conferencing platform spatial.chat. Enhace the scientific reach of our event by contributing your own work! \nPoster presenters are also invited to contribute a 90 second pre-recorded “microtalk”. The microtalks will run on loop in our spatial.chat coffee break space\, serving as an advertisement for your work in the lead up to the poster session. \nRegistration\nPlease visit: https://scmb.gatech.edu/4th-annual-symposium
URL:https://biomath.math.ufl.edu/event/southeast-center-for-mathematics-and-biology-4th-annual-symposium/
LOCATION:Zoom
CATEGORIES:Fall 2021
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