Population-level consequences of the interaction between host stage-structure and disease Multiple life stages are a universal feature of organismal life cycles. Disease impacts life stages differently, and, in some cases, affects only a single stage in a population. Because disease outbreaks are expected to increase worldwide, understanding the population-level consequences of these stage-specific disruptions is …
Minimizing the financial cost of COVID-19 using optimal control The COVID-19 pandemic has already caused hundreds of thousands of deaths worldwide. Countries have implemented national lockdowns in an effort to curtail the loss of human life. Consequently, they have had major economic repercussions due to joblessness and other factors. In an attempt to decrease economic …
Asymptomatic transmission in COVID-19 dynamics Asymptomatic transmission has been critical to the spread of COVID-19, making the disease more difficult to control. However, the bulk of prior work assumes that asymptomatic transmission is fixed over time. Here we explore the coupling between asymptomatic incidence (at the level of individuals) with asymptomatic relevance (at the scale …