Biomathematics

To be rescheduled next semester. Biologically grounded mechanistic modelling from single-cell transcriptomics: case studies in neuroblastoma developmental dynamics and tubular injury in kidney rejection Ordinary differential equation models are ubiquitous in mathematical biology due to their interpretability and tractability. At the same time, their construction relies on substantial a priori assumptions about the relevant variables

Pertussis transmission models and demographic shifts under evolving vaccination programs Pertussis, a highly contagious infection of the respiratory tract, was one of the main causes of child morbidity and mortality in developed countries, in the pre-vaccine era. Following the scale-up and roll-out of childhood vaccination programs in the 1940s–1960s, the incidence and severity of pertussis

Modeling GLP-1 Treatments in Ovulatory Dysfunction GLP-1 receptor agonists (GLP-1 RAs) have gained widespread attention for their effectiveness in treating metabolic abnormalities such as type 2 diabetes and obesity. Central to their success is the regulation of glucose-insulin metabolism and improvement of insulin resistance. In reproductive endocrinology, GLP-1 RAs have also shown promise as off-label