Spatial and temporal dynamics of dengue in southeast Asia Dengue viruses exist as four antigenically distinct serotypes DENV1-DENV4 that interact with each other in multiple immune-mediated mechanisms.  One of these mechanisms, immune-mediated enhancement, through which immunity derived from one serotype leads to either enhanced disease or enhanced viral replication of subsequent infections, has been the focus of

Approximating the probability of invasion in discrete stochastic population models When an individual with a novel trait is introduced in a new environment, we would like to understand what drives the likelihood that its lineage will persist. In deterministic population models, whether the invasive population “succeeds” often depends on whether the parameters of the system

Predicting disease outbreak in models of aquaculture Infectious Salmon Anemia (ISA) virus (ISAv) is an Orthomyxovirus which causes ISA in a variety of finfish including Atlantic salmon (Salmo salar L.).  The disease has resulted in large mortality events and associated economic losses to the salmon culture industries in nearly all major salmon producing countries.  We