Modeling across-scale feedbacks of infectious diseases A current challenge for disease modeling and public health is to understand pathogen dynamics across infection scales from within-host to between-host. Viral and immune response kinetics upon infection impact transmission to other hosts and feedback into population-wide immunity, all of which influence the severity, trajectory, and evolution of a …

Quantifying the effects of vaccines and a booster vaccine dose on the dynamics of COVID-19 in the United States The coronavirus disease 2019 (COVID-19) pandemic continues to have a devastating impact on health systems and economies across the globe, with the USA among the worse impacted nations. Implementing public health measures in tandem with effective …

Using Mathematics to Unravel Mosquito Behavioral Dynamics that Capacitates Malaria Parasite Success in a Human-Mosquito Built Environment Many bottlenecks can hamper a successful malaria parasite transmission from one human to another. For example, a successful transmission of the parasite from humans to mosquitoes and back to humans requires that a susceptible feeding female mosquito successfully …

The impact of vaccination on human papillomavirus infection with disassortative geographical mixing Human papillomavirus (HPV) infection can spread between regions. What is the impact of disassortative geographical mixing on the dynamics of HPV transmission? Vaccination is effective in preventing HPV infection. How to allocate HPV vaccines between genders within each region and between regions to …