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  • Valvanera Vozmediano Esteban

    Valva Vozmediano (UF Pharmacometrics & Systems Pharmacology)

    Zoom To obtain the Zoom link, please contact Youngmin Park at park.y@ufl.edu or Kyle Adams at adams.k@ufl.edu.

    Integrative disease-drug-trial platform for Parkinson’s disease Despite the wide research on Parkinson’s disease (PD), current knowledge on how to link pathophysiological changes and clinical symptoms is still minimal. We are developing an integrative disease-drug-trial platform using different analysis approaches that serves as a quantitative link between (potential) biomarkers of disease progression and clinical scores. This …

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  • Sophia Jang

    Sophia Jang (Texas Tech University, Mathematics and Statistics)

    Zoom To obtain the Zoom link, please contact Youngmin Park at park.y@ufl.edu or Kyle Adams at adams.k@ufl.edu.

    Modeling Resistance in Oncolytic Viral Therapy Drug resistance is a common phenomenon in the treatment of cancer. As with other cancer therapies, treatment failure due to resistance also occurs for the oncolytic viral therapy (OVT). In this talk, we introduce a simple deterministic model of tumor-virus interaction to investigate OVT resistance. The free oncolytic viruses …

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  • Necibe Tuncer

    Necibe Tuncer (Florida Atlantic University, Mathematical Sciences)

    Zoom To obtain the Zoom link, please contact Youngmin Park at park.y@ufl.edu or Kyle Adams at adams.k@ufl.edu.

    Structural and practical identifiability analysis of a multiscale immuno-epidemiological model We perform the identifiability analysis of a multiscale model of seasonal influenza with multiscale data. We show that the well studied target cell limited within-host model is not structurally identifiable. So, we reformulate the model and work with a scaled within-host model which is structurally …

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  • Thomas Angelini

    Thomas E. Angelini (UF Mechanical & Aerospace Engineering)

    217 Little Hall

    Collective Cell Behavior in 3D Cell Assemblies—3D Printed Structures, Random Aggregates, and Perfectly Precise Arrays The remarkable differences between cells grown on plates and cells in vivo or 3D culture are well-known. At the physical level, cell shape, structure, motion, and mechanical behavior in 3D are totally different from those in the dish and are …

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  • Hayriye Gulbudak

    Hayriye Gulbudak (University of Louisiana at Lafayette, Mathematics)

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    Multi-Scale Models of Infectious Disease Dynamics and Validating with Data The bidirectional feedback induced through population and individual-level infectious disease and host immune dynamics requires development of innovative multi-scale models. In this talk, I will introduce structured nonlinear partial differential equation models linking immunology and epidemiology, along with novel stability analysis and computational tools for …

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  • Thomas Hillen

    Thomas Hillen (University of Alberta, Mathematical and Statistical Sciences)

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    Modelling Microtube Driven Invasion of Glioma Malignant gliomas are highly invasive brain tumors. Recent attention has focused on their capacity for network-driven invasion, whereby mitotic events can be followed by the migration of nuclei along long thin cellular protrusions, termed tumour microtubes (TM). Here I develop a mathematical model that describes this microtube-driven invasion of …

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  • Melody Walker

    Melody Walker (UF Laboratory for Systems Medicine)

    235 Little Hall

    Modeling the effects of Aedes aegypti's larval environment on population and disease spread Mosquitoes vector harmful pathogens that infect millions of people every year, and developing approaches to effectively control mosquitoes is a topic of great interest. However, the success of many control measures is highly dependent upon ecological, physiological, and life history traits of …

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  • John Dallon

    John Dallon (Brigham Young University, Mathematics)

    235 Little Hall

    Modeling Mesenchymal Cell Motion - Force, Speed and the Role of Focal Adhesion Lifetimes In this talk I will present a force based mathematical model of mesenchymal cell motion where adhesion sites are randomly placed and have a probabilistically determined lifespan. Numerical simulations and theoretical results will be discussed and compared to experimental data. The …

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  • Meghan Ferrall-Fairbanks

    Meghan Ferrall-Fairbanks (UF Biomedical Engineering)

    235 Little Hall

    Tumor Composition and the Host Environment on Cancer Treatment Strategies The one-size-fits-all approach is not effective at treating cancer and tumor heterogeneity plays an important role in patient response. Current dogma characterizes tumor heterogeneity resulting from compounding genetic and epigenetic changes and instability, ultimately driving unfavorable outcomes for these patients. However, some cancers, including many …

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  • Daniel Cruz

    Daniel Cruz (UF Laboratory for Systems Medicine)

    235 Little Hall

    Estimating the Long-term Behavior of Biologically Inspired Agent-based Models An agent-based model (ABM) is a computational model in which the local interactions of autonomous agents with each other and with their environment give rise to global properties within a given domain. The use of ABMs in biology has become widespread over the last few years …

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