Bistability between acute and chronic states in a Model of Hepatitis B Virus Dynamics Understanding the mechanisms responsible for different clinical outcomes following hepatitis B infection requires a systems investigation of dynamical interactions between the virus and the immune system. To help elucidate mechanisms of protection and those responsible from transition from acute to chronic
Insights into oscillatory neural dynamics using a phase-amplitude framework Model reduction techniques can provide useful insight into the dynamics behaviour of high dimensional oscillatory systems such as networks of neurons or neural field models. However, the utility of the classical technique of phase reduction is limited by the assumption that the local dynamics for each
Mathematical modeling of CD8 T cell search for malaria infection in the liver Malaria, a disease caused by parasites of the Plasmodium genus, begins when Plasmodium-infected mosquitoes inject malaria sporozoites while searching for blood. Sporozoites migrate from the skin via blood to the liver, infect hepatocytes, and form liver stages. In mice, sufficient numbers of
