Image analysis and agent-based modeling of tumor-immune interactions in the glioblastoma microenvironment Glioblastoma is a highly aggressive and deadly brain cancer with no current treatment options available that can achieve remission. One potential explanation for minimally effective treatments is the ability of gliomas to take advantage of processes within the body's immune system to infiltrate
An approximate Bayesian computation approach for embryonic astrocyte migration model reduction During embryonic development of the retina of the eye, astrocytes, a type of glial cell, migrate over the retinal surface and form a dynamic mesh. This mesh then serves as scaffolding for blood vessels to form the retinal vasculature network that supplies oxygen and
Discovering dynamical patterns of activity from single-trial intracranial EEG recordings In this talk I will discuss a data-driven method that leverages time-delayed coordinates, diffusion maps, and dynamic mode decomposition, to identify neural features in large scale brain recordings that correlate with subject-reported perception. The method captures the dynamics of perception at multiple timescales and distinguishes
