A stochastic first-order reaction gene translation and nuclear-to-cell ratio homeostasis model Cell size varies between different cell types, and between different growth and osmotic conditions. However, the nuclear-to-cell volume ratio …
Understanding the effect of white matter delays on large scale brain dynamics The presence of myelin is a powerful structural factor that controls the conduction velocity of mammalian axons. It …
High-Order Accuracy Computation of Coupling Functions for Strongly Coupled Oscillators We develop a general framework for identifying phase reduced equations for finite populations of coupled oscillators that is valid far …
Modelling intermediate filaments – from filament elongation to network organization Intermediate filaments (IFs) constitute a crucial component of the cytoskeleton, playing vital roles in maintaining cell shape, mechanical integrity, and …
Mathematical Optimization of Drug Regimens Improvements in drug regimens can make a difference in both clinical trial success and patient outcomes. Optimal control can be used to mathematically optimize regimens, …
Simplifying Soil Organic Carbon Model Structures with First-Order Linear Decay: When, How, and Why? Soil organic matter is the largest terrestrial pool of carbon on Earth, containing more carbon than …
Turing Patterns as a Model for Brain Folding Development Neuroscientists are interested in correlating brain function with anatomy. However, the highly complex folding patterns of the brain and the high …
The Eye-Lens Growth Model Biological lens in the eye of a mammal focuses light on the retina. Its shape and size is crucial for that purpose. We provide the first …
Chaos and homeostasis in multiple timescales dynamics Complex nonlinear and network dynamics, as observed in many biological systems, are prone to generate complex chaotic activity. Fortunately, in nature, these systems …
Cytoneme-mediated morphogenesis Morphogen protein gradients play an essential role in the spatial regulation of patterning during embryonic development. The most commonly accepted mechanism of protein gradient formation involves the diffusion …
