Chaos and homeostasis in multiple timescales dynamics Complex nonlinear and network dynamics, as observed in many biological systems, are prone to generate complex chaotic activity. Fortunately, in nature, these systems …
Cytoneme-mediated morphogenesis Morphogen protein gradients play an essential role in the spatial regulation of patterning during embryonic development. The most commonly accepted mechanism of protein gradient formation involves the diffusion …
Unraveling Lassa Fever Persistence: A Compartmental Model with Environmental Virus-Host-Vector Interaction Lassa fever (LF), a severe viral hemorrhagic disease transmitted by rodents, particularly Mastomys natalensis, is endemic in West Africa, notably …
Sensitivity, Bifurcation, and Stochastic Analysis of Tuberculosis Progression Mycobacterium tuberculosis infection features various disease outcomes: clearance, latency, active disease, and latent tuberculosis infection (LTBI) reactivation. Identifying the decisive factors for …
Optimal control of combination immunotherapy in a glioblastoma-immune dynamics model Glioblastoma (GBM) is the most common type of primary brain tumor. It is very aggressive with minimally effective treatment options. …
Data Assimilation in Medical Models and Digital Twins One of the growing areas of interest in the context of biological and medical models is the question of how to personalize …
NPIs, vaccination, and collective action under social norms Social dynamics are an integral part of the spread of disease affecting contact rates as well as the adoption of pharmaceutical and non-pharmaceutical …
Discovering dynamical patterns of activity from single-trial intracranial EEG recordings In this talk I will discuss a data-driven method that leverages time-delayed coordinates, diffusion maps, and dynamic mode decomposition, to …
An approximate Bayesian computation approach for embryonic astrocyte migration model reduction During embryonic development of the retina of the eye, astrocytes, a type of glial cell, migrate over the retinal …
Image analysis and agent-based modeling of tumor-immune interactions in the glioblastoma microenvironment Glioblastoma is a highly aggressive and deadly brain cancer with no current treatment options available that can achieve …
